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Melorheostosis
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Melorheostosis is a progressive skeletal disorder that causes bones to thicken.[1] This condition can also affect joints, soft tissue, and skin. Melorheostosis can cause pain, stiffness, limited movement, and limb deformities, although some individuals do not have any symptoms. Mutations in the LEMD3 gene have been found to cause melorheostosis.[2] Treatment options include surgery, physical and occupational therapy, hydrotherapy, and medications.[1]

References
  1. Melorheostosis Association Brochure. Melorheostosis Association Web site. Available at: http://www.melorheostosis.com/default_files/Page329.htm. Accessed November 3, 2009.
  2. Azouz ME, Greenspan A. . Orphanet Encyclopedia. February 2005;:. Available at: http://www.orpha.net/data/patho/GB/uk-Melorheostosis.pdf. November 3, 2009.

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More Detailed Information (Found 4 resources)
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    • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
    • The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Melorheostosis. Click on the link to go to OMIM and review these resources.
    • Orphanet is a database dedicated to information on rare diseases and orphan drugs.  Access to this database is free of charge.  Click on the link to read information on this topic.
    • PubMed is a searchable database of medical literature and lists journal articles that discuss Melorheostosis. Click on the link to view a sample search on this topic.
 
NLM Gateway (Found 1 resource)
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    • NLM Gateway allows users to search many resources offered on the National Library of Medicine's Web site at once to quickly find more information about this condition. Some of the resources may be a duplicate of the resources listed on this page. To search NLM Gateway, click on the link; the condition name will already be in the search box, so you can just click the “Search” button.
 
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    • The National Organization of Rare Disorders (NORD) has partnered with Inspire.com to launch an online community for people with rare diseases called The NORD Rare Disease Community. This community connects medical patients, family members, caregivers, and professionals. Click on The NORD Rare Disease Community to learn more.
    • RareShare is an online social hub dedicated to patients, families and healthcare professionals affected by rare medical disorders. Click on RareShare to learn more.
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