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Tietze syndrome


Other Names for this Disease

  • Chondropathia tuberosa
  • Costochondral junction syndrome
  • Tietze's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

What is Tietze syndrome?

What are the signs and symptoms of Tietze syndrome?

What causes Tietze syndrome?

How is Tietze syndrome diagnosed?

How might Tietze syndrome be treated?

What is the long-term outlook for people with Tietze syndrome?

What is Tietze syndrome?

Tietze syndrome is an inflammatory condition characterized by chest pain and swelling of the cartilage that joins the upper ribs to the breastbone (costochondral junction). Signs and symptoms of this condition usually develop in young adults (before age 40) and include mild to severe chest pain that may extend into the arms and/or shoulders. The cause of this condition is unknown. In some cases, Tietze syndrome may resolve on its own without treatment. Management for others may include minimizing physical activity; applying local heat; and taking pain medications and/or nonsteroidal anti-inflammatory drugs.[1][2]

Of note, this syndrome is different from Tietz syndtrome, which is characterized by profound hearing loss from birth, fair skin, and light-colored hair.[3]
Last updated: 11/11/2014

What are the signs and symptoms of Tietze syndrome?

The signs and symptoms of Tietze syndrome usually develop in young adulthood (before age 40). The most common symptom is mild to severe chest pain that may extend into the arms and/or shoulders. The onset of pain can be gradual or sudden and may worsen with coughing, sneezing, or deep breathing.[2][1]

More than 70% of cases occur on only one side (unilateral) and affect one joint. The affected joint is typically tender and swollen. While the pain associated with Tietze syndrome usually subsides after several weeks or months, the swelling may persist.[2]
Last updated: 11/11/2014

What causes Tietze syndrome?

The exact underlying cause of Tietze syndrome is currently unknown. Some researchers have speculated that small injuries to the anterior chest wall may contribute to the development of the condition.[2]
Last updated: 11/11/2014

How is Tietze syndrome diagnosed?

Tietze syndrome is a diagnosis of exclusion. This means that a diagnosis is made in people with chest pain and swelling of the cartilage that joins the upper ribs to the breastbone (costochondral junction) after other conditions with similar signs and symptoms have been ruled out. A thorough physical exam and various tests (i.e. electrocardiogram, x-ray, CT scan) may be necessary to exclude other conditions.[2]
Last updated: 11/11/2014

How might Tietze syndrome be treated?

In some individuals, the pain associated with Tietze syndrome resolves on its own without any treatment. Management options for others may include avoidance of strenuous activity; applying local heat; taking pain medications and/or nonsteroidal anti-inflammatory drugs; and receiving local corticosteroid injections. Although the pain usually subsides after several weeks or months, swelling may persist.[4][2][1]
Last updated: 11/11/2014

What is the long-term outlook for people with Tietze syndrome?

The long-term outlook for people with Tietze syndrome is generally good. Most people are not severely affected by this condition and life expectancy is normal.[2]
Last updated: 11/11/2014

References
  1. Tietze syndrome. NORD. April 16, 2008; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/637/viewAbstract. Accessed 9/23/2013.
  2. Gijsbers E, Knaap SF. Clinical presentation and chiropractic treatment of Tietze syndrome: A 34-year-old female with left-sided chest pain. J Chiropr Med. March 2011; 10(1):60-63.
  3. MITF. Genetics Home Reference (GHR). 2006; http://ghr.nlm.nih.gov/gene=mitf. Accessed 1/28/2010.
  4. Liu NYN, Canoso JJ. Periarticular Rheumatic Disorders. In: Greene HL, Levinson W, Modest GA, Mulrow CD, Scherger JE, Young MJ. Noble: Textbook of Primary Care Medicine, 3rd ed. Philadelphia, PA: Mosby; 2001;


Other Names for this Disease
  • Chondropathia tuberosa
  • Costochondral junction syndrome
  • Tietze's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.