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Genetic and Rare Diseases Information Center (GARD)

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Tietze syndrome

Other Names for this Disease
  • Chondropathia tuberosa
  • Costochondral junction syndrome
  • Tietze's syndrome
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Tietze syndrome is an inflammatory condition characterized by chest pain and swelling of the cartilage that joins the upper ribs to the breastbone (costochondral junction). Signs and symptoms may include mild to severe pain, which can begin gradually or suddenly; the pain may worsen due to sneezing, coughing or strenuous activity. In some cases, pain may spread to the neck, shoulders or arms. While the exact cause of Tietze syndrome is not known, some cases may occur secondary to other disorders such as psoriatic arthritis. It is generally considered a benign condition and may resolve on its own without treatment. Management may include minimizing physical activity; applying local heat; and taking pain medications and/or nonsteroidal anti-inflammatory drugs. Tietze syndrome is sometimes confused with a similar condition called costochondritis which is characterized by painful, tender, but non-swollen costochondral joints.[1][2]
Last updated: 9/24/2013


  1. Tietze syndrome. NORD. April 16, 2008; Accessed 9/23/2013.
  2. Gijsbers E, Knaap SF. Clinical presentation and chiropractic treatment of Tietze syndrome: A 34-year-old female with left-sided chest pain. J Chiropr Med. March 2011; 10(1):60-63.
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Basic Information

  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

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