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Genetic and Rare Diseases Information Center (GARD)

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Florid cemento-osseous dysplasia


Other Names for this Disease
  • FCOD
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Overview



What is florid cemento-osseous dysplasia?

What are the signs and symptoms of florid cemento-osseous dysplasia?

What causes florid cemento-osseous dysplasia?

How is florid cemento-osseous dysplasia diagnosed?

How might florid cemento-osseous dysplasia be treated?


What is florid cemento-osseous dysplasia?

Florid cemento-osseous dysplasia is characterized by lesions in the upper and/or lower jaw that occur when normal bone is replaced with a mix of connective tissue and abnormal bone.[1] It tends to affect middle aged women, particularly women of African American and Asian descent.[1] The lesions often affect both sides of the jaw and are symmetrical. The number, size, and shape of the lesions vary. Occasionally the lesions expand and may cause discomfort, pain, or mild disfigurement. The radiographic appearance of the lesions are important for diagnosis.[1][2]

Last updated: 6/22/2010

What are the signs and symptoms of florid cemento-osseous dysplasia?

Usually florid cemento-osseous dysplasia causes no signs or symptoms and is identified incidentally during a radiograph taken for some other purpose.[2] Occasionally however, the lesions expand causing discomfort, pain, and/or mild disfigurement.[2]
Last updated: 6/22/2010

What causes florid cemento-osseous dysplasia?

The cause of florid cemento-osseous dysplasia is not known. This condition is usually not familial (i.e., does not tend to run in families), however a rare familial form has been described in a few families. In these families the condition affected younger individuals, and the rate of lesion growth was rapid.[2][3]
Last updated: 6/22/2010

How is florid cemento-osseous dysplasia diagnosed?

Diagnosis of cemento-osseous dysplasia relies on the radiographic findings of the lesions as well as the clinical signs and symptoms. Careful assessment and examination must be made to differentiate cemento-osseous dysplasia from other lesions with similar appearance, namely Paget's disease, chronic diffuse sclerosing osteomyelitis, fibrous dysplasia, osteosarcoma, periapical cemental dysplasia.[1][2]
Last updated: 6/22/2010

How might florid cemento-osseous dysplasia be treated?

In many cases florid cemento-osseous dysplasia does not require treatment, however careful follow-up may be warranted.[2] When the condition causes discomfort, pain, or disfigurement, the treatment plan is tailored to the patient. The following article describes the treatment of florid cemento-osseous dysplasia in one patient. We recommend that you speak with your dentist to learn more about your treatment options and for referrals to local specialists.

Minhas G, Hodge T, Gill DS. Orthodontic treatment and cemento-osseous dysplasia: a case report. J Orthod. 2008 Jun;35(2):90-5.

You can also use the following tools to help you find specialists in your area.

The Academy of General Dentistry has a tool for finding member dentists in your area. 
http://www.knowyourteeth.com/findadentist/

The American Association of Oral and Maxillofacial Surgeons offers the following tool for finding member oral and maxillofacial surgeons in your area.
http://www.aaoms.org/findoms.php

Sometimes with more rare diseases, it can be helpful to have an evaluation with a specialist at a major university hospital or academic medical center. Such facilities often have access to up-to-date testing and technology, a large group of health care providers and specialists to consult with, and research opportunities.
Last updated: 3/17/2010

References
  1. Singer SR, Mupparapu M, Rinaggio J. J Am Dent Assoc. 2005 Jul; http://jada.ada.org/cgi/content/full/136/7/927. Accessed 3/17/2010.
  2. Minhas G, Hodge T, Gill DS. J Orthod. 2008 Jun; http://jorthod.maneyjournals.org/cgi/content/full/35/2/90. Accessed 3/17/2010.
  3. Gigantiform Cementoma, Familial. Online Mendelian Inheritance in Man. 2008; http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=137575. Accessed 3/17/2010.