Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Epithelioid sarcoma

See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Epithelioid sarcoma is a rare cancer that most often occurs in the soft tissue of the fingers, hands and forearms of young adults.[1]  It may also be found in the legs, trunk, head or neck regions.  It is rare in young children and adults, and it occurs more frequently in men.[2][3]  Epithelioid sarcoma begins as a painless, firm growth or bump that may be accompanied by an open wound (ulceration) in the skin covering the growth.[3]  It is considered an aggressive cancer because it has a high chance of regrowing after treatment (a recurrence), or spreading to surrounding tissues or more distant parts of the body (a metastasis).[3]  Epithelioid sarcoma is first treated with surgery to remove all the cancer cells (wide local excision).[2][3]  Amputation of part of the affected limb may be needed in severe cases.[1]  Radiation therapy or chemotherapy may also be used to destroy any cancer cells not removed during surgery.[2]
Last updated: 9/16/2011


  1. Nagoshi N, Anazawa U, Morioka H, Mukai M, Yabe H, Toyama Y. Epithelioid sarcoma arising on the forearm of a 6-year-old boy: case report and review of the literature. Pediatric Surgery International. 2006; 22:771-773. Accessed 9/13/2011.
  2. Pai KK, Pai SB, Sripathi H, Pranab, Rao P. Epithelioid sarcoma: a diagnostic challenge. Indian Journal of Dermatology, Venereology and Leprology. 2006; 72:446-448. Accessed 9/13/2011.
  3. Armah HB, Parwani AV. Epithelioid Sarcoma. Archives of pathology & Laboratory Medicine. 2009; 133:814-819. Accessed 9/13/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

2 question(s) from the public on Epithelioid sarcoma have been answered. See questions and answers. You can also submit a new question.

Basic Information

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Epithelioid sarcoma. Click on the link to view a sample search on this topic.