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Other Names for this Disease
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 Normally the level of COHb is less than 1-2% in adults. People with Hb Zurich tend to have COHb levels above 3%. The health effects of Hb Zurich tend to be mild compared to other inherited blood cell disorders. Symptoms usually develop only when the body is stressed due to an infection or fever or when exposed to certain drugs. Symptoms develop as a result of the premature breakdown of RBC (hemolytic anemia). Click here to visit MedlinePlus.gov and view an illustration of hemoglobin.Hemoglobin (Hb) Zurich is an inherited blood disorder. People with Hb Zurich have an abnormal form of Hb, a red blood cell (RBC) protein that binds to oxygen in the lungs. This abnormal Hb more readily binds to carbon monoxide (producing carboxyhemoglobin or COHb).
Last updated: 3/20/2014
- Steinberg MH. Unstable hemoglobin variants. In: Basow M. UpToDate. Waltham, MA: UpToDate; 2014; Accessed 3/20/2014.
- Steinberg MH, Orget BG, Higgs DR, Veatherall DJ. Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management. Oxford: Cambridge University; August 2009; Accessed 3/20/2014.
- Benz EJ Jr, Ebert BL. Hemoglobin Variants Associated With Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias. In: Hoffman. Hematology: Basic Principles and Practice, 6th ed. 2012; Accessed 3/20/2014.
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- PubMed is a searchable database of medical literature and lists journal articles that discuss Hemoglobin Zurich. Click on the link to view a sample search on this topic.