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* Not a rare disease
* Not a rare disease
Other Names for this Disease
- Age-related macular degeneration
- Age-related maculopathy
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macula. The macula is located in the retina in the eye and enables one to see fine details and perform tasks that require central vision, such as reading and driving. Signs and symptoms include vision loss, which usually becomes noticeable in a person's sixties or seventies and tends to worsen over time. There are 2 major types of AMD, known as the dry form and the wet form. The dry form accounts for up to 90% of cases and is characterized by slowly progressive vision loss. The wet form is associated with severe vision loss that can worsen rapidly. AMD is caused by a combination of genetic and environmental factors, some of which have been identified. Increasing age is the most important non-genetic risk factor. The condition appears to run in families in some cases. While there is currently no cure for AMD, there are therapies available to help slow the progression of the condition.Age-related macular degeneration (AMD) is an eye condition characterized by progressive destruction of the
Last updated: 10/7/2013
- Age-related macular degeneration. Genetics Home Reference. June 2011; http://ghr.nlm.nih.gov/condition/age-related-macular-degeneration. Accessed 10/7/2013.
Your Questions Answeredby the Genetic and Rare Diseases Information Center
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- Genetics Home Reference (GHR) contains information on Macular degeneration. This website is maintained by the National Library of Medicine.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic. Click on the link to view this information.
- The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. Click on the link to view information on this topic.
In Depth Information
- The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Macular degeneration. Click on the link to go to OMIM and review these resources.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Macular degeneration. Click on the link to view a sample search on this topic.