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Genetic and Rare Diseases Information Center (GARD)

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Mannose-binding lectin protein deficiency


* Not a rare disease
Other Names for this Disease
  • Mannose-binding protein deficiency
  • MBL deficiency
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How might mannose-binding lectin protein (MBL) deficiency be treated?

Currently, there are no specific therapies available for mannose-binding lectin protein deficiency. Fresh frozen plasma may be used in emergencies to replace complement components. Routine vaccinations may be recommended (e.g., meningococcal vaccine, pneumococcal vaccine). Because a certain gene has been found to cause this condition, gene therapy may be a viable treatment in the future.[1]
Last updated: 4/9/2012

  1. Agrawal R. Complement deficiency. eMedicine. May 2009; Accessed 1/9/2012.