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Genetic and Rare Diseases Information Center (GARD)

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Dermal eccrine cylindroma

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Your Question

My sister and I have neurofibromas and dermal eccrine cylindromas. Do you have ANY information on these tumors or know where I can get more information? 

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What is a neurofibroma?

A neurofibroma is a non-cancerous (benign) tumor that develops from the cells and tissues that cover nerves.[1] Some people who develop neurofibromas have a genetic condition known as neurofibromatosis (NF). There are different types of NF, but type 1 is the most common.
Last updated: 6/6/2012

What is neurofibromatosis type 1?

Neurofibromatosis type 1 (NF1) is an inherited condition characterized by changes in skin coloring (pigmentation) and the growth of tumors along nerves in the skin, brain, and other parts of the body. The signs and symptoms of this condition vary widely among affected people. Mutations in the NF1 gene cause neurofibromatosis type 1. This condition is considered to have an autosomal dominant pattern of inheritance.[2]
Last updated: 11/9/2011

Where can I find more information on neurofibromas?

More information on neurofibromas is available from the following resources:

Children's Hospital of Boston

The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), has an information page on neurofibromatosis.

You can also contact NINDS for information on neurofibromatosis:

NIH Neurological Institute
P.O. Box 5801
Bethesda, MD 20824
Toll-free:  800-352-9424
Phone: 301-496-5751
TTY: 301-468-5981
E-mail form:
Web site:

Last updated: 9/16/2008

What is a dermal eccrine cylindroma?

Dermal eccrine cylindromas are non-cancerous (benign) sweat gland tumors.[3] They most commonly occur on the head and neck and rarely become cancerous (malignant). "Dermal" indicates that these tumors are found on the skin. An eccrine gland is a type of simple sweat gland that is found in almost all regions of the skin.[4]  Solitary cylindromas occur sporadically and typically are not inherited.[3] They usually begin to form during mid-adulthood as a slow-growing, rubbery nodule that causes no symptoms. The development of multiple cylindromas can be hereditary and is inherited in an autosomal dominant manner.[3]  Individuals with the inherited form begin to develop numerous, rounded nodules of various size shortly after puberty. The tumors grow very slowly and increase in number over time.
Last updated: 9/16/2008

Where can I find more information on dermal eccrine cylindromas?

An article from eMedicine Journal provides information on cylindromas at the following link. You may need to register to view the article, but registration is free.
Last updated: 9/16/2008

See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.