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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Dermal eccrine cylindroma


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Overview


Dermal eccrine cylindromas are non-cancerous (benign) sweat gland tumors.[1] They most commonly occur on the head and neck and rarely become cancerous (malignant). "Dermal" indicates that these tumors are found on the skin. An eccrine gland is a type of simple sweat gland that is found in almost all regions of the skin.[2]  Solitary cylindromas occur sporadically and typically are not inherited.[1] They usually begin to form during mid-adulthood as a slow-growing, rubbery nodule that causes no symptoms. The development of multiple cylindromas can be hereditary and is inherited in an autosomal dominant manner.[1]  Individuals with the inherited form begin to develop numerous, rounded nodules of various size shortly after puberty. The tumors grow very slowly and increase in number over time.
Last updated: 9/16/2008

References

  1. Scheinfeld NS, Mokashi A, Celebi JT, Oppenheim AR. Cylindroma. eMedicine Journal. March 13, 2008; http://www.emedicine.com/DERM/topic94.htm. Accessed 9/16/2008.
  2. Dictionary of cancer terms. National Cancer Institute Web site. http://www.cancer.gov/templates/db_alpha.aspx?CdrID=393531. Accessed 9/16/2008.
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