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Acquired hemophilia

Other Names for this Disease
  • Acquired haemophilia
  • Hemophilia, acquired
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Acquired hemophilia is a rare form of hemophilia in which the body makes specialized proteins called autoantibodies that attack and disable coagulation factors (proteins in the blood that assist with the clotting process).[1] The most common coagulation factor attacked is coagulation factor VIII, though other coagulation factors, including factor V and factor IX have been associated with the condition.[2] The production of autoantibodies is sometimes associated with pregnancy, immune system disorders (e.g., systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome), viral infections cancer, or allergic reactions to certain drugs.[1][2] In about half of cases, the cause of acquired hemophilia is unknown.[1] Treatment may vary from person to person.
Last updated: 12/5/2008


  1. Hemophilia. Genetics Home Reference. May 2010; Accessed 6/16/2011.
  2. Zeitler H, Ulrich-Merzenich G, Hess L, Konsek E, Unkrig C, Walger P, et al. Blood. 2005; Accessed 10/14/2008.
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