Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Immunoglobulin G deficiency

*


* Not a rare disease
Other Names for this Disease
  • IgG deficiency
  • IgG subclass deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview


Immunoglobulin G (IgG) deficiency is a condition that involves the immune system and is characterized by a shortage of type G antibodies.[1] There are four different subclasses of IgG: IgG1, IgG2, IgG3, and IgG4. People with IgG deficiency may have a decreased amount of one or more of the IgG subclasses. When people also have a shortage of other types of antibodies, they are said to have a combined immunodeficiency. Individuals with IgG deficiency may have an increased susceptibility to infection, but the symptoms of this condition are variable.[2] Some people never experience any symptoms. Treatment may involve antibiotics and intravenous (IV) immunoglobulin.[2]
Last updated: 11/11/2008

References

  1. Vafaie J. Immunoglobulin G deficiency. eMedicine Journal. Mar 22, 2005; http://www.emedicine.com/med/TOPIC1161.HTM. Accessed 11/11/2008.
  2. IgG Subclass Deficiency. National Primary Immunodeficiency Resource Center. http://www.info4pi.org/patienttopatient/index.cfm?section=patienttopatient&content=syndromes&area=8. Accessed 11/11/2008.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Immunoglobulin G deficiency. We will answer your question and update these pages with new resources and information.

Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Immunoglobulin G deficiency. Click on the link to view a sample search on this topic.