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Genetic and Rare Diseases Information Center (GARD)

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Goblet cell carcinoid

Other Names for this Disease
  • Goblet cell carcinoma
  • Mucinous carcinoid
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What are the signs and symptoms of goblet cell carcinoid?

The most common first signs in individuals with goblet cell carcinoid are acute appendicitis, abdominal pain and/or a lower abdominal palpable mass.[1] Symptoms of appendicitis may include pain and/or swelling in the abdomen; loss of appetite; nausea and vomiting; constipation or diarrhea; inability to pass gas; and/or a low fever.[2][3]

Other signs and symptoms may include bowel obstruction, intussusception, gastrointestinal bleeding, and chronic intermittent lower abdominal pain. Rare presentations have reportedly included mesenteric adenitis, and iron deficiency anemia due to cecal ulceration.[1]
Last updated: 6/25/2013

  1. Paromita Roy and Runjan Chetty. Goblet cell carcinoid tumors of the appendix: An overview. World J Gastrointest Oncol. June 15, 2010; 2(6):251–258. Accessed 6/25/2013.
  2. Plöckinger U, Couvelard A, Falconi M, Sundin A, Salazar R, Christ E, de Herder WW, Gross D, Knapp WH, Knigge UP, Kulke MH, Pape UF; Frascati. Consensus Conference participants. Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated tumour/carcinoma of the appendix and goblet cell carcinoma. Neuroendocrinology. Epub 2007 Oct 11 -7;
  3. Byrn JC, Wang JL, Divino CM, Nguyen SQ, Warner RR. Management of goblet cell carcinoid. J Surg Oncol. 2006 Oct 1;