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Genetic and Rare Diseases Information Center (GARD)

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Goblet cell carcinoid


Other Names for this Disease
  • Goblet cell carcinoma
  • Mucinous carcinoid
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Overview


Goblet cell carcinoid (GCC)is a rare type of neuroendocrine tumor that involves the appendix almost exclusively. It typically comes to attention in the fifth to sixth decade of life. Signs and symptoms may include acute appendicitis, followed by abdominal pain and a mass. In about fifty percent of affected females, the tumor has metastasized to the ovary by the time of diagnosis. In general, approximately 76% of individuals with a GCC are alive five years after the diagnosis. Prognosis largely depends on the stage of the disease (i.e. the size of the tumor and whether it has spread to other parts of the body). Treatment often includes appendectomy and right hemicolectomy, followed by adjuvant chemotherapy in some cases. However, there is some debate about the extent of surgical treatment for these tumors.[1]
Last updated: 6/25/2013

References

  1. Paromita Roy and Runjan Chetty. Goblet cell carcinoid tumors of the appendix: An overview. World J Gastrointest Oncol. June 15, 2010; 2(6):251–258. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998842/. Accessed 6/25/2013.
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Basic Information

  • The American Cancer Society has an information page on gastrointestinal carcinoid tumor. Click on American Cancer Society to view the information page.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic. 
  • The Carcinoid Cancer Foundation, Inc. has an information page on carcinoid tumors and related neuroendocrine tumors. Click on Carcinoid Cancer Foundation, Inc. to view the information page.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.