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Microcystic adnexal carcinoma

Other Names for this Disease
  • MAC
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Microcystic adnexal carcinoma is a rare tumor of the skin that most often develops in the head and neck region, particularly in the middle of the face, though it may occur in the skin of other parts of the body as well.[1]  The average age of diagnosis is 56.[2]  This tumor is often first noticed as a bump or yellowish spot in the skin.  Though microcystic adnexal carcinomas frequently grow into and disturb nearby tissues and is therefore considered an invasive cancer, this type of tumor rarely spreads to more distant parts of the body (metastasizes).[1] The main treatment for microcystic adnexal carcinoma is Mohs micrographic surgery, which is thought to improve the chances that all of the tumor cells are removed during surgery.[2][1]
Last updated: 7/18/2012


  1. Wetter R, Goldstein GD. Microcystic adnexal carcinoma: a diagnostic and therapeutic challenge. Dermatologic Therapy. 2008; 21:452-458. Accessed 11/4/2011.
  2. Snow S, Madjar DD, Hardy S, Bentz M, Lucarelli MJ, Bechard R, Aughenbaugh W, McFadden T, Sharata H, Dudley C, Landeck A. Microcystic adnexal carcinoma: report of 13 cases and review of the literature. Dermatologic Surgery. 2001; 27:401-408. Accessed 11/4/2011.
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