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Genetic and Rare Diseases Information Center (GARD)

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Other Names for this Disease
  • Adamantinoma
  • Adamantinomatous tumor
  • Craniopharyngeal duct tumor
  • Dysodontogenic epithelial tumor
  • Rathke's pouch tumor
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A craniopharyngioma is a slow-growing benign tumor that develops near the pituitary gland (a small endocrine gland at the base of the brain) and the hypothalamus (a small cone-shaped organ connected to the pituitary gland by nerves).[1][2][3] This tumor most commonly affects children between 5 and 10 years of age; however, adults can sometimes be affected.[1] Craniopharyngiomas are thought to arise from remnants of the craniopharyngeal duct and/or Rathke cleft or from metaplasia (abnormal transformation of cells) of squamous epithelial cell remnants of the stomadeum.[orphanet] Craniopharyngioma is treated with surgery alone or by surgery followed by radiation.[4]

Last updated: 4/3/2009


  1. Blackman S. Craniopharyngioma. MedlinePlus. 2004; Accessed 4/3/2009.
  2. General Information About Childhood Craniopharyngioma. National Cancer Institute (NCI). 2009; Accessed 4/3/2009.
  3. Garnett MR, Puget S, Grill J, Sainte-Rose C. Craniopharyngioma. Orphanet. 2007; Accessed 4/3/2009.
  4. Bobustuc GC, Groves MD, Fuller GN, DeMonte FN. Craniopharyngioma: Treatment & Medication. eMedicine. 2006; Accessed 4/3/2009.
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