See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
neural tube defect in which both the brain and spinal cord remain open; both anencephaly and spina bifida (from the cervical region to the lumbar or sacral region of the spine) are present. Fetuses with craniorachischisis often miscarry during pregnancy or die shortly after birth. The cause is thought to be multifactorial, which means that a combination of genetic and non-genetic factors play a role.Craniorachischisis is the most severe type of
Last updated: 11/5/2013
- Craniorachischisis. Orphanet. January, 2010; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=63260. Accessed 11/4/2013.
- Johnson KM, Suarez L, Felkner MM, Hendricks K. Prevalence of craniorachischisis in a Texas-Mexico border population. Birth Defects Res A Clin Mol Teratol. February, 2004; 70(2):92-94. Accessed 11/5/2013.
Your Questions Answeredby the Genetic and Rare Diseases Information Center
Please contact us with your questions about Craniorachischisis. We will answer your question and update these pages with new resources and information.
On this page
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Craniorachischisis. Click on the link to view a sample search on this topic.