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Genetic and Rare Diseases Information Center (GARD)

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Juvenile Huntington disease

Other Names for this Disease
  • Huntington disease, juvenile onset
  • JHD
  • Juvenile onset HD
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How might Juvenile Huntington disease (HD) be treated?

Physicians may prescribe a number of medications to help control emotional and movement problems associated with HD. It is important to remember however, that while medicines may help keep these clinical symptoms under control, there is no treatment to stop or reverse the course of the disease. Anticonvulsant drugs are usually prescribed to help prevent and control the seizures that occur in children with Juvenile HD.[1] Tetrabenazine is often used to treat chorea. Antipsychotic drugs, such as haloperidol, or other drugs, such as clonazepam, may also help to alleviate chorea and may also be used to help control hallucinations, delusions, and violent outbursts. For depression, physicians may prescribe fluoxetine, sertraline, nortriptyline, or other drugs. Tranquilizers can help control anxiety and lithium may be prescribed to combat severe mood swings.[2]
Last updated: 3/15/2011

  1. Martha Nance, MD. A Guide for Families and Caregivers – Second Edition. The Juvenile HD Handbook. 2007; Accessed 3/15/2011.
  2. Huntington Disease. National Institute of Neurological Disorders and Stroke (NINDS). August 2010; Accessed 3/15/2011.

Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.

Clinical Trials & Research for this Disease

  • lists trials that are studying or have studied Juvenile Huntington disease. Click on the link to go to to read descriptions of these studies.
  • The Huntington Study Group (HSG) is a non-profit group of clinical investigators from medical centers in the United States, Canada, Europe, Australia, New Zealand and South America, experienced in the care of Huntington patients and dedicated to clinical research of Huntington disease (HD).  Click on the link to learn more about research trials that are currently underway.