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Genetic and Rare Diseases Information Center (GARD)

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Myxopapillary ependymoma

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Your Question

My wife was diagnosed by MRI with probable myxopapillary ependymoma. The specialist is recommending surgery; are there any other treatment options?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

How might myxopapillary ependymoma be treated?

Standard treatment of myxopapillary ependymoma is aggressive surgery. It can generally can be cured by gross total surgical resection, and there is usually a favorable prognosis. However, surgery is typically less curative in tumors that are large, multifocal or extend outside the thecal sac. Late recurrences may occur, particularly in pediatric individuals.[1] Treatment strategies may also include radiation, but the use of chemotherapy remains more controversial; chemotherapy has been widely used in pediatric individuals due to more aggressive disease in these individuals.[2] The role of adjuvant chemotherapy or radiotherapy is unclear for the subset of individuals with recurrence or in individuals in whom gross total resection cannot be achieved.[1]
Last updated: 6/8/2011