Other Names for this Disease
- Cerebral astroblastoma
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Astroblastoma is a rare glial tumor usually located in the cerebral hemisphere of the brain. It can occur in individuals of any age, but occurs predominantly in children and young adults. Signs and symptoms depend on the location and size of the tumor but most commonly include headaches and seizures. Because these tumors are rare, there is little known regarding their behavior and how they should be managed. Gross total resection (complete removal) of the tumor is recommended and is associated with a good prognosis for low-grade tumors. Adjuvant therapy, including radiation and/or chemotherapy, is recommended for high-grade and recurrent cases (although its effectiveness is controversial).
Last updated: 9/4/2012
Whether a particular astroblastoma is technically non-cancerous or cancerous (malignant) depends on the histological findings (examination of the affected tissue under a microscopic) in each tumor. Malignant astroblastomas are generally characterized by higher cellularity (the number of its constituent cells) and proliferation; necrosis (death of cells or tissues); and vascular proliferation (growth of blood vessels within the tumor).
Last updated: 9/4/2012
- Agarwal V, Mally R, Palande DA, Velho V. Cerebral astroblastoma: A case report and review of literature. Asian J Neurosurg. April 2012; 7(2):98-100. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410171/. Accessed 9/4/2012.
- John D. Port, Daniel J. Brat, Peter C. Burger and Martin G. Pomper. Astroblastoma: Radiologic-Pathologic Correlation and Distinction from Ependymoma. AJNR. February 2002; 23:243-247.
- Sughrue ME et al. Clinical features and post-surgical outcome of patients with astroblastoma. J Clin Neurosci. June 2011; 18(6):750-754.
- Andrew D Norden, Milan G Chheda, Patrick Y Wen. Uncommon Brain Tumors. UpToDate. Waltham, MA: UpToDate; July 2012;