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Duane syndrome type 3

Other Names for this Disease
  • Duane retraction syndrome 3
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Duane syndrome type 3 is a disorder of eye movement. The affected eye, or eyes, has limited ability to move both inward toward the nose and outward toward the ears. The eye opening narrows and the eyeball pulls in when looking inward toward the nose. About 15 percent of all cases of Duane syndrome are type 3.[1] Most cases occur without other signs and symptoms. In most people with Duane syndrome type 3, the cause is unknown; but it can sometimes be caused by mutations in the CHN1 gene and inherited in an autosomal dominant fashion.[2]
Last updated: 11/18/2011


  1. Learning About Duane Syndrome. National Human Genome Research Institute (NHGRI). September 2010; Accessed 11/18/2011.
  2. Isolated Duane retraction syndrome. Genetics Home Reference. March 2009; Accessed 11/18/2011.
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In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Duane syndrome type 3. Click on the link to view a sample search on this topic.