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Genetic and Rare Diseases Information Center (GARD)

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Bone marrow necrosis


* Not a rare disease
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What is the typical prognosis (chance of recovery) of people with bone marrow necrosis?

Prognosis of people with bone marrow necrosis depends on the age of the patient and associated disease. Children with acute lymphoblastic leukemia (ALL) and bone marrow necrosis appear to have the same prognosis as children with ALL without the necrosis.[1] Adults with bone marrow necrosis associated with a non-cancerous condition, may have a better chance of complete recovery and long term survival than adults with bone marrow necrosis associated with a blood cancer.[2] It can be hard to distinguish bone marrow necrosis due to a drug or condition like disseminated intravascular coagulation versus an underlying cancer. This can make prognosis difficult to predict.
Last updated: 4/8/2010

  1. Inoue S, Monga R, Onwuzurike N. Bone Marrow Necrosis as a presenting feature of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer. 2007;
  2. Matsue K, Takeuchi M, Koseki M, Uryu H. Bone marrow necrosis associated with the use of imatinib mesylate in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia. Ann Hematol. 2006;