Bone marrow necrosis
* Not a rare disease
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Signs and symptoms of bone marrow necrosis, include bone pain, fever, fatigue, and jaundice. The bone pain may be throughout the body or localized to the lower back and/or legs. Laboratory findings may include anemia, thrombocytopenia, and elevated levels of lactic dehydrogenase and alkaline phosphatase.
Last updated: 4/8/2010
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- Matsue K, Takeuchi M, Koseki M, Uryu H. Bone marrow necrosis associated with the use of imatinib mesylate in a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia. Ann Hematol. 2006;
- Inoue S, Monga R, Onwuzurike N. Bone Marrow Necrosis as a presenting feature of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer. 2007;