Other Names for this Disease
- Arterial calcification due to CD73 deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
mutations in the NT5E gene. It is inherited in an autosomal recessive manner.ACDC, or aterial calcification due to CD73 deficiency, is a rare, adult-onset vascular disorder. Individuals with ACDC have calcium buildup in their arteries below the waist and in the joints of their hands and feet but not in the arteries of their heart. Affected individuals can experience progressive pain and cramping in the calves, thighs, buttocks and feet due to poor circulation. ACDC is caused by
Last updated: 2/25/2011
- St Hilaire C, Ziegler SG, Markello TC, Brusco A, Groden C, et.al. NT5E mutations and arterial calcifications. N Engl J Med http://www.ncbi.nlm.nih.gov/pubmed/21288095. February 3, 2011;
Your Questions Answeredby the Genetic and Rare Diseases Information Center
Please contact us with your questions about ACDC. We will answer your question and update these pages with new resources and information.
In Depth Information
- PubMed is a searchable database of medical literature and lists journal articles that discuss ACDC. Click on the link to view a sample search on this topic.
- NIH researchers identify genetic cause of new vascular disease.
Rare disease is first discovered in Undiagnosed Diseases Program