Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Bilateral frontoparietal polymicrogyria

Other Names for this Disease
  • BFPP
  • Cerebellar ataxia with neuronal migration defect
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

What are the signs and symptoms of bilateral frontoparietal polymicrogyria?

The most commonly reported signs and symptoms in individuals with bilateral frontoparietal polymicrogyria (BFPP) include moderate to severe intellectual disability; motor and cognitive developmental delay; seizures; cerebellar dysfunction; and dysconjugate gaze (eyes that are not aligned). Other findings that have been reported include increased muscle tone; mild truncal ataxia (decreased ability to perform smoothly coordinated voluntary movements); finger dysmetria (difficulty controlling speed, distance and/or power of movements); and strabismus.

In addition to polymicrogyria, brain MRI studies may show enlarged ventricles, reduced white matter volume (showing areas containing nerve fibers), patchy white matter signal changes, and underdevelopment of the cerebellum and brainstem.[1]
Last updated: 8/24/2011

  1. Cassandra L. Kniffin. POLYMICROGYRIA, BILATERAL FRONTOPARIETAL. OMIM. March 27, 2006; Accessed 8/24/2011.