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Genetic and Rare Diseases Information Center (GARD)

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MYH-associated polyposis


Other Names for this Disease

  • Autosomal recessive familial adenomatous polyposis
  • MAP syndrome
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Overview

MYH-associated polyposis is an inherited condition characterized by the development of multiple adenomatous colon polyps and an increased risk of colorectal cancer.[1][2] This condition, a milder form of familial adenomatous polyposis (FAP), is sometimes called autosomal recessive familial adenomatous polyposis because it is inherited in an autosomal recessive manner. People with this condition have fewer polyps than those with the classic type of FAP; fewer than 100 polyps typically develop, rather than hundreds or thousands.[2] They may also be at increased risk for upper gastrointestinal polyps.[1] MYH-associated polyposis is caused by mutations in the MYH gene.[1][2]
Last updated: 6/28/2011

References

  1. MYH-Associated Polyposis. Cancer.Net. September 2010; http://www.cancer.net/patient/Cancer+Types/MYH-Associated+Polyposis. Accessed 6/28/2011.
  2. Familial adenomatous polyposis. Genetics Home Reference (GHR). April 2008; http://ghr.nlm.nih.gov/condition/familial-adenomatous-polyposis. Accessed 6/28/2011.
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Basic Information

  • Genetics Home Reference (GHR) contains information on MYH-associated polyposis. This website is maintained by the National Library of Medicine.
  • The Johns Hopkins Cancer Risk Assessment Program provides information about polyposis and MYH gene. Click on the link to go access this information.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic. 

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss MYH-associated polyposis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Autosomal recessive familial adenomatous polyposis
  • MAP syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.