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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Lichen planus pigmentosus

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Other Names for this Disease
  • Lichen planus pigmentosa
  • Lichen planus pigmentosus inversus
  • LP pigmentosa
  • LP pigmentosus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Your Question

Is this a cancerous disease, and how do I treat this condition? I am desperate.

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

Is lichen planus pigmentosus a cancerous condition?

Lichen planus pigmentosus (LPP) is not a type of cancer and is generally not associated with an increased risk for cancer. However, one case of LPP has been reported in association with Bazex syndrome and head and neck cancer.[1][2]

It has been recognized that other types of lichen planus are rarely associated with cancer. For example, bullous lichen planus, a rare form of lichen planus in which blisters form within the characteristic papules, is the subtype that is most frequently linked with cancer.[2] A risk for oral cancer (approximately .5-2%) has also been reported in people affected by oral lichen planus.[3]
Last updated: 4/10/2015

How might lichen planus pigmentosus be treated?

Treatment for lichen planus pigmentosus is generally symptomatic and may include:[4][5]
  • Topical (applied to the skin) corticosteroids
  • Topical calcineurin inhibitors (medications that are typically used to treat eczema)
  • Skin lightening agents
  • Laser therapy
Last updated: 4/9/2015

References
  • Lichen planus pigmentosus. Orphanet. May 2011; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=254463. Accessed 2/27/2012.
  • Sassolas B, Zagnoli A, Leroy JP, Guillet G. Lichen planus pigmentosus associated with acrokeratosis of Bazex. Clin Exp Dermatol. January 1994; 19(1):70-73.
  • Supic G, Kozomara R, Zeljic K, Stanimirovic D, Magic M, Surbatovic M, Jovic N, Magic Z. HMGB1 genetic polymorphisms in oral squamous cell carcinoma and oral lichen planus patients. Oral Dis. 2015. January 2015; [Epub ahead of print]:
  • Neelam Vashi, MD; Roopal Kundu, MD. Approach to the patient with hyperpigmentation disorders. UpToDate. January 2015; Accessed 4/9/2015.
  • Han XD, Goh CL. A case of lichen planus pigmentosus that was recalcitrant to topical treatment responding to pigment laser treatment. Dermatol Ther. September-October 2014; 27(5):264-267.
Other Names for this Disease
  • Lichen planus pigmentosa
  • Lichen planus pigmentosus inversus
  • LP pigmentosa
  • LP pigmentosus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.