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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Lichen planus pigmentosus


Other Names for this Disease
  • Lichen planus pigmentosa
  • Lichen planus pigmentosus inversus
  • LP pigmentosa
  • LP pigmentosus
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Treatment


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How might lichen planus pimentosus be treated?

There is currently no treatment proven effective for lichen planus pigmentosus (LPP).[1] Vitamin A therapy reportedly has been successful in some affected individuals.[2] Authors of a study published in 2010 reported that they noted positive treatment results in some affected individuals who used topical tacrolimus ointment. They reported that they found significant clearance of the condition after 8 weeks of treatment in 7 of 13 affected individuals. They believe that tacrolimus might have some role in the treatment of LPP, but it needs to be studied further on more individuals from different parts of the world.[1]
Last updated: 2/29/2012

References
  1. Al-Mutairi N, El-Khalawany M.. Clinicopathological characteristics of lichen planus pigmentosus and its response to tacrolimus ointment: an open label, non-randomized, prospective study. J Eur Acad Dermatol Venereol. May 2010; 24(5):535-540.
  2. KH Mohan. Acquired macular hyperpigmentation an overview. Journal of Pakistan Association of Dermatologists. 2011; 21:43-54.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Lichen planus pigmentosus. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.