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Genetic and Rare Diseases Information Center (GARD)

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Systemic capillary leak syndrome

Other Names for this Disease
  • Capillary leak syndrome
  • Capillary leak syndrome with monoclonal gammopathy
  • Clarkson disease
  • Periodic systemic capillary leak syndrome
  • SCLS
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Your Question

Is there a full and final cure for systemic capillary leak syndrome?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

How might systemic capillary leak syndrome be treated?

Unfortunately, there is no cure for systemic capillary leak syndrome at this time.  However, recent studies suggest that taking medication known as beta-adrenergic agonists (including terbutaline) or undergoing immunoglobulin intravenous (IV) therapy may reduce the frequency of attacks and may increase survival in individuals affected with this condition.[1]
Last updated: 8/30/2012

  • Gousseff M, Arnaud L, Lambert M, Hot A, Hamidou M, Duhaut P, Papo T, Soubrier M, Ruivard M, Malizia G, Tieulié N, Rivière S, Ninet J, Hatron PY, Amoura Z; Capillary Leak Syndrome Registry. The systemic capillary leak syndrome: a case series of 28 patients from a European registry. Annals of Internal Medicine. 2011; 154:464-471. Accessed 8/28/2012.