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Systemic capillary leak syndrome
Other Names for this Disease
- Capillary leak syndrome
- Capillary leak syndrome with monoclonal gammopathy
- Clarkson disease
- Periodic systemic capillary leak syndrome
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 Attacks frequently last for several days and require emergency care. Most cases of capillary leak occur randomly in previously healthy adults. Treatment involves preventing attacks using medications which may decrease capillary leakage and interfere with hormones that may cause future leakage. Once an attack is underway, treatment is aimed at controlling blood pressure to maintain blood flow to vital organs and prevention of swelling due to fluid accumulation. Capillary leak syndrome may lead to multiple organ failure, shock and even death. Systemic capillary leak syndrome is a condition in which fluid and proteins leak out of tiny blood vessels and flow into surrounding tissues, resulting in dangerously low blood pressure.
Last updated: 8/30/2012
- Dictionary of Cancer Terms: capillary leak syndrome. National Cancer Institute (NCI). http://www.cancer.gov/dictionary?CdrID=426421. Accessed 8/27/2012.
- Greipp PR. Systemic Capillary Leak Syndrome. National Organization for Rare Disorders (NORD). 2008; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1106/viewAbstract. Accessed 8/27/2012.
- Druey KM, Greipp PR. Narrative Review: The Systemic Capillary Leak Syndrome. Annals of Internal Medicine. 2010; http://www.annals.org/content/153/2/90.full.pdf+html. Accessed 8/27/2012.
- The National Cancer Institute glossary of terms includes an entry for capillary leak syndrome with monoclonal gammopathy. Click on National Cancer Institute to view the definition.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
In Depth Information
- MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Systemic capillary leak syndrome. Click on the link to view a sample search on this topic.