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Genetic and Rare Diseases Information Center (GARD)

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Frontal fibrosing alopecia

Other Names for this Disease
  • FFA
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How might frontal fibrosing alopecia be treated?

Unfortunately, there is no proven cure for frontal fibrosing alopecia (FFA).[1]  However, because hair loss in frontal fibrosing alopecia (FFA) is thought to be caused by inflammation of hair follicles, treatment often involves using anti-inflammatory medications or ointments, such as corticosteroids or hydroxychloroquine (brand name Plaquenil), to reduce inflammation and suppress the body's immune system.[2]  One study of 36 individuals with FFA found a significant reduction in symptoms after six months of hydroxychloroquine treatment; however, they found minimal benefit to continuing hydroxychloroquine treatment after six months.[3]  Researchers continue to question whether or not treatment is effective, or if hair loss in FFA stops naturally.[4]
Last updated: 4/9/2012

  1. Frontal fibrosing alopecia. DermNet NZ. August 2011; Accessed 4/9/2012.
  2. Frequently Asked Questions. Cicatricial Alopecia Research Foundation. September 2011; Accessed 8/9/2013.
  3. Samrao A, Chew AL, Price V. Frontal fibrosing alopecia: a clinical review of 36 patients. British Journal of Dermatology. 2010; 163:1296-1300. Accessed 4/9/2012.
  4. Tan KT, Messenger AG. Frontal fibrosing alopecia: clinical presentations and prognosis. British Journal of Dermatology. 2009; 160:75-79. Accessed 4/9/2012.

Clinical Trials & Research for this Disease

  • lists trials that are studying or have studied Frontal fibrosing alopecia. Click on the link to go to to read descriptions of these studies.