Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Gray zone lymphoma

Other Names for this Disease
  • Mediastinal gray zone lymphoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Gray zone lymphoma is a cancer of the immune system.  The name of this lymphoma refers to the fact that cancer cells in this condition are in a "gray zone" (an uncertain category) because they appear similar to that of two other types of lymphoma, classical Hodgkin lymphoma and mediastinal large B-cell lymphoma.  Because features of gray zone lymphoma overlap with these two other types of lymphoma, diagnosing this condition can be difficult.  Gray zone lymphoma is most often diagnosed in young adults when an unusual lump (mass) is found in the chest in the space between the lungs (mediastinum).  This condition affects men and women equally.[1]
Last updated: 5/17/2012


  1. Traverse-Glehen A, Pittaluga S, Gaulard P, Sorbara L, Alonso MA, Raffeld M, Jaffe ES. Mediastinal gray zone lymphoma: the missing link between classic Hodgkin's lymphoma and mediastinal large B-cell lymphoma. American Journal of Surgical Pathology. 2005; 29:1411-1421. Accessed 5/12/2012.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Gray zone lymphoma have been answered. See questions and answers. You can also submit a new question.
On this page

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Gray zone lymphoma. Click on the link to view a sample search on this topic.