Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Hypomyelination with atrophy of basal ganglia and cerebellum


Other Names for this Disease
  • H-ABC
  • HABC
  • HLD6
  • Leukodystrophy, hypomyelinating, 6
  • Leukodystrophy, hypomyelinating, with atrophy of the basal ganglia and cerebellum
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Cause


Newline Maker

What causes hypomyelination with atrophy of basal ganglia and cerebellum (H-ABC)?

The exact cause of hypomyelination with atrophy of basal ganglia and cerebellum (H-ABC) is not yet known.  However, H-ABC is a type of leukodystrophy, and most leukodystrophies are caused by changes (mutations) in certain genes.  Therefore, some researchers have suggested that H-ABC may also have a genetic cause.[1]
Last updated: 3/28/2012

References
  1. Schiffmann R, van der Knaap MS. The latest on leukodystrophies. Current opinion in neurology. 2004; 17:187-192. http://www.ncbi.nlm.nih.gov/pubmed/15021247. Accessed 3/27/2012.