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Genetic and Rare Diseases Information Center (GARD)

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Superior limbic keratoconjunctivitis

Other Names for this Disease
  • SLK
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What causes superior limbic keratoconjunctivitis (SLK)?

The cause of SLK is unknown. It has been theorized that this condition causes swelling of the superior bulbar conjunctiva (the clear layer that covers the eyeball, over the sclera) resulting in friction between the upper eyelid and the eyeball. Superior limbic keratoconjunctivitis has been associated with thyroid abnormalities (usually hyperthyroidism), contact lens wear, graft versus host disease, and preservatives from ophthalmologic medications.[1][2]
Last updated: 7/24/2012

  1. Oakman JH. Superior Limbic Keratoconjunctivitis. Medscape Reference. August 26, 2011; Accessed 7/23/2012.
  2. Papaliodis GN. Superior Limbic Keratoconjunctivitis. The Ocular Immunology and Uveitis Foundation. Accessed 7/23/2012.