Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Chronic graft versus host disease

Other Names for this Disease
  • Chronic GVHD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Chronic graft versus host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient's body.[1] Symptoms may include skin rash, mouth sores, dry eyes, liver inflammation, development of scar tissue in the skin and joints, and damage to the lungs.[1][2] The exact cause of chronic GVHD is unknown.[2] It likely results from a complex immune-mediated interaction between the donor and recipient cells.[2][3] Chronic GVHD is treated with prednisone or other similar anti-inflammatory or immunosuppressive medications.[1][2]  
Last updated: 2/21/2013


  1. Graft-versus-host disease. MedlinePlus. June 2012; Accessed 2/21/2013.
  2. Chronic Graft-versus-host disease. Chronic Graft Versus Host Disease Consortium. Accessed 2/21/2013.
  3. Mandanas RA. Graft Versus Host Disease. Medscape Reference. December 2012; Accessed 2/21/2013.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Chronic graft versus host disease. We will answer your question and update these pages with new resources and information.

Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Chronic graft versus host disease. Click on the link to view a sample search on this topic.