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Autoimmune polyglandular syndrome type 3

Other Names for this Disease
  • APS3
  • Autoimmune polyendocrine syndrome type 3
  • PAS3
  • Polyglandular autoimmune syndrome type 3
More Names
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Overview


Autoimmune polyglandular syndrome (APS) type 3 is an autoimmune condition that affects the body's endocrine glands. The syndrome, which typically affects women during middle age, results from failure of the glands to produce their hormones. This condition is characterized by autoimmune thyroiditis along with another organ-specific autoimmune disease.[1][2][3] The other autoimmune diseases may include diabetes mellitus, pernicious anemia, vitiligo, alopecia, myasthenia gravis, and Sjogren's syndrome.[2] The adrenal cortex (the outer layer of the adrenal gland) is not involved.[1][2][3] There are three types of autoimmune polyglandular syndrome type 3:[1][2] 

References

  1. Aung K. Type III Polyglandular Autoimmune Syndrome. Medscape Reference. http://emedicine.medscape.com/article/124398-overview. Accessed January 15, 2013.
  2. Cihakova D. Polyglandular Autoimmune syndrome Type 3 (PAS 3) . Johns Hopkins Medical Institutions: Autoimmune Disease Research Center. http://autoimmune.pathology.jhmi.edu/diseases.cfm?systemID=3&DiseaseID=68. Accessed January 15, 2013.
  3. Tariq SH. Polyglandular Deficiency Syndromes. The Merck Manual. http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/polyglandular_deficiency_syndromes/polyglandular_deficiency_syndromes.html. Accessed January 15, 2013.
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General Information

  • The Johns Hopkins Medical Institute Web site has an information page titled "Polyglandular Autoimmune Syndrome Type 3 (PAS-3)." Click on the link above to view this information page.
  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.  Click on the link to read information on this topic.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Autoimmune polyglandular syndrome type 3. Click on the link to view a sample search on this topic.