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Genetic and Rare Diseases Information Center (GARD)

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Linear and whorled nevoid hypermelanosis


Other Names for this Disease
  • Linear and whorled hypermelanosis
  • LWNH
  • Nevoid hypermelanosis, linear and whorled
  • Reticulate hyperpigmentation of Iijima
  • Zebra-like hyperpigmentation
More Names
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Overview


Linear and whorled nevoid hypermelanosis is a skin condition characterized by swirling streaks of hyperpigmented (darkened) skin. The hyperpigmentation follows the lines of Blashko. The hyperpigmentation often occurs alone, but additional symptoms have been described in individual cases. Its occurrence is nearly always sporadic. The cause of linear and whorled nevoid hypermelanosis is not known.[1]
Last updated: 3/18/2013

References

  1. Maruani A, Khallouf R, Machet MC, Lorette G. Diffuse linear and whorled nevoid hypermelanosis in a newborn. J Pediatr. 2012 Jan;160(1):171; http://www.ncbi.nlm.nih.gov/pubmed/21868034. Accessed 3/18/2013.
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Basic Information

  • The New Zealand Dermatological Society Incorporated provides information on the lines of Blaschko on their DermNet Web site. Click on the link to view the information page.
  • MedlinePlus.gov, the National Library of Medicine Web site designed to help you research your health questions, provides information on pigmentation disorders. Click on MedlinePlus.gov to view the information page.

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Linear and whorled nevoid hypermelanosis. Click on the link to view a sample search on this topic.

Resources for Kids

  • Kids Skin Health, a American Academy of Dermatology's web site, provides kids, teens, and parents with information on skin conditions. Click on Kids Skin Health to access this Web site.