Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Multifocal motor neuropathy

See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

What causes multifocal motor neuropathy?

Multifocal motor neuropathy is caused by abnormal activity of the body's immune system.[1] Most people with this neuropathy have detectable autoantibodies. Autoantibodies are antibodies that mistakenly target and damage specific tissues or organs of the body.[2] One or more autoantibodies may be produced by a person's immune system when it fails to distinguish between "self" and "non-self" proteins.[2] The most common autoantibody detected in people with multifocal motor neuropathy is anti-GM1 IgM.[1]
Last updated: 5/1/2013

  1. Guimarães-Costa R, Bombelli F, Léger JM. Multifocal motor neuropathy. Presse Med. 2013 Apr 24; Accessed 5/1/2013.
  2. American Association for Clinical Chemistry. Autoantibodies. LabTestsOnline. January 12, 2012; Accessed 5/1/2013.