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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Brittle diabetes


Other Names for this Disease
  • Brittle diabetes mellitus
  • Brittle type 1 diabetes
  • Labile diabetes
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Symptoms


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What are the symptoms of brittle diabetes?

The main symptom of brittle diabetes is severe instability of blood glucose levels with frequent and unpredictable episodes of hypoglycemia and/or ketoacidosis that cause a disruption of daily activities. Three clinical presentations have been described:[1]

Patients with brittle diabetes have wide swings in their blood sugar levels and often experience differing blood sugar responses to the same dose and type of insulin. Complications such as neuropathy, nephropathy, and retinopathy are common. Most patients are females in their twenties of thirties, though any age or gender can be affected.[1]

Last updated: 9/26/2013

References
  1. McCulloch DK. The adult patient with brittle diabetes mellitus. UpToDate. August 17, 2012; http://www.uptodate.com/contents/the-adult-patient-with-brittle-diabetes-mellitus?detectedLanguage=en&source=search_result&search=brittle+diabetes&selectedTitle=1%7E6&provider=noProvider. Accessed 8/8/2013.