Juvenile amyotrophic lateral sclerosis
Other Names for this Disease
- Amyotrophic lateral sclerosis, juvenile
- Amyotrophic lateral sclerosis type 2
- Amyotrophic lateral sclerosis type 4
- Amyotrophic lateral sclerosis type 5
Juvenile amyotrophic lateral sclerosis (ALS) is a type of motor neuron disease which leads to problems with muscle control and movement. Signs and symptoms of juvenile ALS tend to present by age 25 years or younger. Unlike other types of ALS, juvenile ALS is not rapidly progressive. People with juvenile ALS can have a normal life expectancy. Juvenile ALS is often genetic and may be inherited in an autosomal dominant or autosomal recessive fashion.
- Amyotrophic Lateral Sclerosis. Genetics Home Reference Web site. August 2007; http://ghr.nlm.nih.gov/condition=amyotrophiclateralsclerosis. Accessed 2/7/2008.
- Donkervoort S, Siddique T. Amyotrophic Lateral Sclerosis. GeneReviews . 2009; http://www.ncbi.nlm.nih.gov/books/NBK1450/. Accessed 4/12/2011.
- Orban P, Devon RS, Hayden MR, Leavitt BR. Juvenile Amyotrophic Lateral Sclerosis. Handbook of Clinical Neurology. . 2007;82(3):301-312; http://www.ncbi.nlm.nih.gov/pubmed/18808900. Accessed 7/8/2013.
- Rabin BA, Griffin JW, Crain BJ, Scavina M, Chance PF, Cornblath DR. Brain . Autosomal dominant juvenile amyotrophic lateral sclerosis. Brain. 1999;122(8):1539-1550; http://brain.oxfordjournals.org/content/122/8/1539.long. Accessed 7/5/2013.
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- Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Juvenile amyotrophic lateral sclerosis. Click on the link to go to OMIM and review these resources.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Juvenile amyotrophic lateral sclerosis. Click on the link to view a sample search on this topic.