Congenital nephrotic syndrome Finnish type
Other Names for this Disease
- Congenital nephrotic syndrome 1
- Congenital nephrotic syndrome, Finnish type
- Finnish congenital nephrosis
- Nephrosis 1, congenital, Finnish type
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 The syndrome is characterized by nephrotic syndrome (a group of symptoms including protein in the urine (proteinuria), low blood protein levels, high cholesterol levels, and swelling), which progresses rapidly to end-stage kidney disease. Although more commonly seen in individuals of Finnish descent, congenital nephrotic syndrome of Finnish type has been reported worldwide.  Congenital nephrotic syndrome of Finnish type is inherited in an autosomal recessive fashion and is caused by mutations in a gene called NPHS1. At this time, kidney transplantation seems to be the only treatment available for this condition.Congenital nephrotic syndrome of Finnish type is a genetic condition of the kidney that presents in utero or within the first three months of life.
Last updated: 8/31/2009
- Lee BH, Ahn YH, Choi HJ, Kang HK, Kim S, Cho B et al. J Korean Med Sci. 2009; http://jkms.org/Synapse/Data/PDFData/0063JKMS/jkms-24-S210.pdf. Accessed 8/31/2009.
- Nephrotic syndrome. MedlinePlus Medical Encyclopedia. August 14, 2007; http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000490.htm. Accessed 8/31/2009.
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