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Genetic and Rare Diseases Information Center (GARD)

Other Names for this Disease
  • Agenesis of corpus callosum
  • Da silva syndrome
  • Mental retardation hypoplastic corpus callosum preauricular tag
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Corpus callosum agenesis is a birth defect in which the structure that connects the two sides of the brain (the corpus callosum) is partially or completely absent. This birth defect can occur as an isolated condition or in combination with other abnormalities. The effects of agenesis of the corpus callosum range from subtle or mild to severe, depending on associated brain abnormalities. Treatment usually involves management of symptoms and seizures if they occur.[1]
Last updated: 5/4/2009


  1. NINDS Agenesis of the Corpus Callosum Information Page. National Institute of Neurological Disorders and Stroke Website. October 01, 2007; Accessed 5/4/2009.
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