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Genetic and Rare Diseases Information Center (GARD)

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Cryptogenic organizing pneumonia

Other Names for this Disease
  • COP
  • Idiopathic BOOP
  • Idiopathic bronchiolitis obliterans organizing pneumonia
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What causes cryptogenic organizing pneumonia?

The underlying cause of cryptogenic organizing pneumonia (COP) is unknown (it is idiopathic). Organizing pneumonia is more specifically diagnosed as cryptogenic organizing pneumonia (COP) when, among other characteristics, no definite cause (such as infection or underlying tissue disease) for the condition is found. In other words, any known cause for the pneumonia must be ruled out before stating that organizing pneumonia is really cryptogenic.[1]

Other organizing pneumonias may result from infection (bacteria, viruses, parasites, or fungi); drugs; or a reaction to radiation therapy therapy for breast cancer. Organizing pneumonia also may occur in the specific context of specific disorders such as certain connective tissue disorders, ulcerative colitis, or after lung transplantation or bone marrow grafting.[1]
Last updated: 3/18/2013

  1. Cordier JF. Cryptogenic organizing pneumonia. Clin Chest Med. December 2004; 25(4):727-738.