Best vitelliform macular dystrophy
Other Names for this Disease
- Best disease
- Best macular dystrophy
- Early-onset vitelliform macular dystrophy
Your QuestionCan you provide updated information about Best vitelliform macular dystrophy? Are there support organizations or chat rooms that I can visit to connect with others with this diagnosis?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
- What is Best vitelliform macular dystrophy?
- How does Best vitelliform macular dystrophy affect vision?
- What genes are related to Best vitelliform macular dystrophy?
- How do people inherit Best vitelliform macular dystrophy?
- Is there treatment for individuals with Best vitelliform macular dystrophy?
- Are there support organizations or chat rooms that I can visit to connect with others with Best vitelliform macular dystrophy?
Best vitelliform macular dystrophy causes a fatty yellow pigment (lipofuscin) to build up in cells underlying the macula. Over time, the abnormal accumulation of this substance can damage cells that are critical for clear central vision. As a result, people with this disorder often lose their central vision, and their eyesight may become blurry or distorted. Best vitelliform macular dystrophy typically does not affect side (peripheral) vision or the ability to see at night.
Studies have shown that most people with Best vitelliform macular dystrophy retain enough vision for reading and driving in at least one eye into adulthood (88% have 20/40 or better vision). Vision usually deteriorates slowly and does not become significant until after age 40.
Most current research is aimed at understanding the genetic cause of the disorder, which may aid in the development of treatment options.
The following support organizations provide information and support for individuals with Best vitelliform macular dystrophy. Some of these groups have online message boards where individuals can share information.
The Association for Fighting Best Disease
Enbalim St' 27
Association for Macular Disease, Inc.
210 East 64th Street
New York NY 10065
Macular Degeneration Foundation
PO Box 531313
Henderson NV 89053
Foundation Fighting Blindness
11435 Cronhill Drive
Owings Mills MD 21117-2220
Phone: 410-568-0150 (local)
Message board for Best disease: http://www.blindness.org/index.php?option=com_simplestforum&view=postlist&forumId=10&Itemid=161
American Foundation for the Blind
11 Penn Plaza
New York NY 10001
Message board for Best disease: http://www.afb.org/message_board_replies2.asp?TopicID=3334&FolderID=14
- Best Vitelliform Macular Dystrophy. National Organization for Rare Diseases (NORD). 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Best%20Vitelliform%20Macular%20Dystrophy. Accessed 7/28/2009.
- Vitelliform macular dystrophy. Genetics Home Reference (GHR). 2008; http://ghr.nlm.nih.gov/condition=vitelliformmaculardystrophy. Accessed 7/28/2009.
- MacDonald IM, Lee T. Best Vitelliform Macular Dystrophy. GeneReviews. 2009; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=bvd. Accessed 7/28/2009.
- Besch D, Zrenner E. Best disease. Orphanet. 2005; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=1243. Accessed 7/28/2009.
- Altaweel M. Best Disease. eMedicine. February 11, 2010; http://emedicine.medscape.com/article/1227128. Accessed 9/10/2010.
- Best disease. National Center for Biotechnology Information (NCBI). http://www.ncbi.nlm.nih.gov/books/NBK22187/. Accessed 7/29/2009.