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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Best vitelliform macular dystrophy


Other Names for this Disease
  • Best disease
  • Best macular dystrophy
  • BMD
  • BVMD
  • Early-onset vitelliform macular dystrophy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might Best vitelliform macular dystrophy be treated?

There is no specific treatment for Best vitelliform macular dystrophy (BVMD) at this time.[1][2] Low vision aids help affected people with significant loss of visual acuity.[3] Laser photocoagulation, photodynamic therapy, and anti-VEGF (vascular endothelial growth factor) agents such as bevacizumab have shown limited success in treating some of the secondary features of BVMD such as choroidal neovascularization (when abnormal blood vessels grow under the macula and retina).[3][1][2]
Last updated: 2/13/2015

References
  1. Besch D, Zrenner E. Best disease. Orphanet. 2005; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=1243. Accessed 7/28/2009.
  2. Altaweel M. Best Disease. eMedicine. February 11, 2010; http://emedicine.medscape.com/article/1227128. Accessed 9/10/2010.
  3. MacDonald IM, Lee T. Best Vitelliform Macular Dystrophy. GeneReviews. 2009; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=bvd. Accessed 7/28/2009.


Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.

Clinical Trials & Research for this Disease

  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • Best disease
  • Best macular dystrophy
  • BMD
  • BVMD
  • Early-onset vitelliform macular dystrophy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.