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Genetic and Rare Diseases Information Center (GARD)

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Factor V deficiency


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Overview


Factor V deficiency is an inherited blood disorder that involves abnormal blood clotting (coagulation). This disorder is caused by the deficiency of a blood protein called factor V.[1] The reduced amount of factor V leads to episodes of abnormal bleeding that range from mild to severe.[1] Factor V deficiency is inherited in an autosomal recessive manner,[2] which means that both copies of the F5 gene in each cell have mutations.
Last updated: 7/22/2013

References

  1. Matsui W. Factor V deficiency. MedlinePlus Web site. May 3, 2006; http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm. Accessed 3/24/2008.
  2. Factor V deficiency. National Hemophilia Foundation Web site. http://www.hemophilia.org/NHFWeb/MainPgs/MainNHF.aspx?menuid=186&contentid=409&rptname=bleeding. Accessed 3/24/2008.
Your Questions Answered
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1 question(s) from the public on Factor V deficiency have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference contains information on Factor V deficiency. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Heart, Lung, and Blood Institute (NHLBI) can provide information on this topic. You can reach them by calling 301-592-8573 or by E-mail at nhlbiinfo@nhlbi.nih.gov
  • The National Hemophilia Foundation has an information page on factor V deficiency.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Factor V deficiency. Click on the link to view a sample search on this topic.