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Genetic and Rare Diseases Information Center (GARD)

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Fetal and neonatal alloimmune thrombocytopenia

Other Names for this Disease
  • NAIT
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How might fetal and neonatal alloimmune thrombocytopenia (NAIT) be treated?

NAIT is often unexpected and is usually diagnosed after birth. Once suspected, the diagnosis is confirmed by demonstration of maternal anti-platelet antibodies directed against a paternal antigen inherited by the baby. Management in the newborn period involves transfusion of platelets that do not contain the specific antigens. Prompt diagnosis and treatment are essential to reduce the chances of death and disability due to severe bleeding.[1]
Last updated: 6/6/2011

  1. Kaplan C. Fetal and neonatal alloimmune thrombocytopenia. Orphanet. October 2006; Accessed 6/6/2011.