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Freiberg's disease

Other Names for this Disease
  • Freiberg's infraction
  • Freiberg-Kohler syndrome
  • Kohler's second disease
  • Osteochondrosis of the metatarsal head, usually the second
  • Second metatarsal osteochondrosis
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Freiberg's disease is an osteochondrosis of the metatarsal head, most commonly occurring in young athletes older than 12 years who perform on their toes in either sprinting or jumping activities.[1][2] The primary complaint is often a vague forefoot pain, worsened by activity and weight-bearing and relieved with rest.[1] While some cases may resolve spontaneously, patients who do not respond to conservative measures may require surgery.[2][3] The exact cause remains unknown [2]  
Last updated: 3/10/2009


  1. DeeLee JC, Drez D. Freiberg's Disease. DeeLee and Drez's Orthopaedic Sports Medicine, 2nd ed.. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2003;
  2. Canale ST, Beaty JH. Freiberg Infraction. Campbell's Operative Orthopaedics, 11th ed.. Philadelphia, PA: Mosby, An Imprint of Elsevier; 2007;
  3. Boyer M, DeOrio JK. Freiberg Infraction. eMedicine. September 25, 2007; Accessed 3/10/2009.
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