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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Glioblastoma


Other Names for this Disease
  • Glioblastoma multiforme
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Glioblastoma is a malignant (cancerous) brain tumor that develops from a specific type of brain cell called an astrocyte. These cells help support and nourish neurons (nerve cells of the brain) and form scar tissue that helps repair brain damage in response to injury. Glioblastomas are often very aggressive and grow into surrounding brain tissue. Signs and symptoms, such as headache, nausea, vomiting and/or drowsiness, may develop when the tumor begins to put excess pressure on the brain. Affected people may also experience other features depending on the size and location of the tumor. In most cases, the exact underlying cause is unknown; however, they can rarely occur in people with certain genetic syndromes such as neurofibromatosis type 1, Turcot syndrome and Li Fraumeni syndrome. There is currently no cure for glioblastoma. Treatment is palliative and may include surgery, radiation therapy and/or chemotherapy.[1][2][3]
Last updated: 1/19/2015

References

  1. Jeffrey N Bruce, MD. Glioblastoma Multiforme. Medscape Reference. May 2014; http://emedicine.medscape.com/article/283252-overview.
  2. GLIOBLASTOMA MULTIFORME. NORD. May 2009; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/281/viewAbstract.
  3. Adult Brain Tumors Treatment (PDQ®). National Cancer Institute. January 2015; http://www.cancer.gov/cancertopics/pdq/treatment/adultbrain/Patient#_440.
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Basic Information

  • The American Brain Tumer Association has an information page on Glioblastoma. Click on the link to view this information page.
  • The Merck Manual provides information on this condition for patients and caregivers. 
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic.
     
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Merck Manual for health care professionals provides information on Glioblastoma.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Glioblastoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Glioblastoma multiforme
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.