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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Glioblastoma


Other Names for this Disease
  • Glioblastoma multiforme
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might glioblastoma be treated?

Unfortunately, there is no cure for glioblastoma. Treatment is palliative and may include surgery, radiation therapy and/or chemotherapy. The best treatment options for each person depend on many factors including the size and location of the tumor; the extent to which the tumor has grown into the surrounding normal brain tissues; and the affected person's age and overall health. Glioblastoma is often treated with surgery initially to remove as much of the tumor as possible. In most cases, it is not possible to remove the entire tumor so additional treatment with radiation therapy and/or chemotherapy is necessary. In elderly people or people in whom surgery is not an option, radiation therapy and/or chemotherapy may be used.[1][2]
Last updated: 1/20/2015

References
  1. Jeffrey N Bruce, MD. Glioblastoma Multiforme. Medscape Reference. May 2014; http://emedicine.medscape.com/article/283252-overview.
  2. GLIOBLASTOMA MULTIFORME. NORD. May 2009; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/281/viewAbstract.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Glioblastoma. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name Polifeprosan 20 with carmustine
Trade Name
(Manufacturer Name)
Gliadel®
(Eisai)
Indication
The FDA has approved this product to be used in this manner.
As an adjunct to surgery to prolong survival in patients with recurrent glioblastoma multiforme for whom surgical resection is indicated
More Information about this product Drug Information Portal

Other Names for this Disease
  • Glioblastoma multiforme
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.